Process for preparing poly-cationically active polymers from preformed polymers

ABSTRACT

PROCESS FOR PREPARING POLY-CATIONICALLY ACTIVE POLYMERS BY REACTING A PERFORMED POLYMER HAVING HYDROXYL, THIOL, ALKALI METAL ALKOXIDE, ALKALI METAL MERCAPTIDE, CARBOXYLIC ACID OR SULFONIC ACID TERMINAL RADICALS WITH (A) A MONOBASIC ACID WHICH IS STRONGER THAN 100% SULFURIC ACID AND WHICH IS CAPABLE OF EFFECTING THE CATIONIC POLYMERIZATION OF TETRAHYDROFURAN WITHOUT CHAIN TRANSFER, (B) AN ACYL HALIDE THEREOF, (C) AN ANHYDRIDE THEREROF, OR (D) AN ALKYLENE BIESTER OF THE STRUCTURE   DZCH2(A)NCH2ZD   WHERE Z IS OXYGEN OR SULFUR, N IS 0 OR 1, A IS A DIVALENT ORGAIC RADICAL WHICH IS DEVOID OF ACETYLENIC AND OLEFINIC UNSATURATION AND OF ALKYLATABLE GROUPS CONTAINING ZEREWITINOFF HYDROGEN ATOMS AND D IS THE RESIDUE REMAINING AFTER DELETION OF -OH FROM THE ACID GROUP OF (A). IF THE PERFORMED POLYMER HAS ACYL BROMIDE OR ACYL CHLORIDE TERMINAL RADICALS, A PROTENIC ACID WHICH IS STRONGER THAN 100% SULFURIC ACID AND WHICH IS CAPABLE OF EFFECTING THE CATIONIC POLYMERIZATION OF TETRAHYDROFURAN WITOUT CHAIN TRANSFER, OR A SALT THEREOF, CAN BE USED AS THE COREACTANT. THE PRODUCTS OF THE PROCESS ARE CATIONICALLY ACTIVE AND &#34;LIVING&#34; AT EACH END OF THE POLYMER CHAIN.

United States Patent Office 3,824,197 PROCESS FOR PREPARING POLY-CATIONICAL- LY ACTIVE POLYMERS FROM PREFORMED POLYMERS Samuel Smith, Roseville, and Allen J. Hubin, White Bear Lake, Minn., assignors to Minnesota Mining and Manufactoring Company, St. Paul, Minn.

No Drawing. Application Feb. 10, 1966, Ser. No. 527,399,

which is a continuation-impart of abandoned application Ser. No. 290,218, June 24, 1963. Divided and this application June 23, 1970, Ser. No. 51,448

Int. 'Cl. C08g 39/00 US. Cl. 260-2 D 7 Claims ABSTRACT OF THE DISCLOSURE Process for preparing poly-cationically active polymers by reacting a preformed polymer having hydroxyl, thiol, alltali metal alkoxide, alkali metal mercaptide, carboxylic acid or sulfonic acid terminal radicals with (a) a monobasic acid which is stronger than 100% sulfuric ac d and which is capable of effecting the cationic polymerization of tetrahydrofuran without chain transfer, (b) an acyl halide thereof, (c) an anhydride thereof, or (d) an alkylene biester of the structure where Z is oxygen or sulfur, n is or 1, A is a divalent orgamc radical which is devoid of acetylenic and olefinic unsaturation and of alkylatable groups containing Zerewitmotf hydrogen atoms and D is the residue remaining after deletion of -OH from the acid group of (a). If the preformed polymer has acyl bromide or acyl chloride terminal radicals, a protonic acid which is stronger than 100% sulfuric acid and which is capable of effecting the cationic polymerization of tetrahydrofuran without chain transfer, or a salt thereof, can be used as the coreactant. The products of the process are cationically active and living at each end of the polymer chain.

This application is a division of US. patent application Ser. No. 527,399, filed on Feb. 10, 1966, which is a continuation-in-part of US. Patent Application Ser. No. 290,- 218, filed June 24, 1963, and now abandoned.

This invention relates to new polymeric materials having unique reactivity of a poly-cationic nature. In one aspect this invention relates to polymers having high reactivity as alkylating or acylating agents, as reffected by their ability to engage in electrophilic displacement reactions with various compounds. In still another aspect this invention relates to a method for the preparation of new polymeric materials, including block copolymers, polymeric polyamines, polymeric polythiols, polymeric polyisocyanates, bisphenols containing a polymeric bridge, and other polymeric derivatives.

In the polymer field considerable effort has been expended in an attempt to provide polymeric materials having a high degree of reactivity. Such reactivity is particularly desirable to permit modification of physical and chemical properties, e.g. to improve the adhesion of the polymer to metals and glass, to carry out further chemical reactions such as simple substitution, crosslinking, chain extension, graft and block copolymerization, etc. These efforts to achieve the desired reactivity in the polymer molecule have met with only limited success. The preparation of reactive polymers having an anionic character has recently been reported, and the term living polymers has been ascribed to such polymers, as noted by M. Szware et al. in the Journal of the American Chemica'l Society, vol. 78, page 2656 (1956). Polymers having such living character behave as though they are nonterminated.

The present invention provides living polymers of a poly-cationic nature which are quite stable in the presence of oxygen, as contrasted to the anionic living polymers which tend to add oxygen in the presence of air and thus lose their living character. Another important distinction between cationic and anionic living polymers is the ability of the former to polymerize further in the presence of certain cationically polymerizable monomers. The cationic and anionic living polymers differ markedly in their reaction with compounds containing active (i.e. Zerewitinoff) hydrogen atoms. Living polymers of an anionic nature attack such compoundsin a nucleophilic manner, i.e. a proton is transferred to the polymer to form an inactive, non-functional polymer, whereas the cationic living polymers attack such compounds in an electrophilic manner to produce macromolecules containing functional substituents and a free proton. This important distinction is evidenced by the reaction of the respective living polymers with ammonia. If living polymers of anionic character react at all with ammonia, they form the protonated, non-functional polymer plus the free amide ion; whereas the cationic living polymers of this invention react with ammonia to form the functional polymeric amine or amide plusa free proton. The reaction of the living polymers of this invention with ammonia (or amines) is a remarkably facile reaction proceeding at temperatures usually below 25 C. and at atmospheric pressure to give quantitative conversions to the alkylated or acylated amines. Thus, the poly-cationically active polymers are distinguished by their alkylating and acylating ability.

It is therefore an object of this invention to provide new and useful polymers, particularly polymers having a high degree of poly-cationic activity.

'Another object of this invention is to provide polymeric alkylating and acylating agents.

Still another object of this invention is to provide a method for the preparation of polymers having living characteristics from cationically polymerizable monomers and for the preparation of derivatives thereof.

A further object of this invention is to prepare polycationically active polymers from preformed polymers.

Yet another object of this invention is to provide novel functionally substituted polymers.

It is also an object of this invention to provide methods for the preparation of block copolymers and resins useful in the preparation of tough chain extended and cured products.

Other objects and advantages of this invention, as well as the characteristics of the polymers and processes of this invention, will be apparent from the following deperature of 25 C. or lower is employed, proceeds rapidly to produce polymeric polyprimary polyamines or polyamides in which the indicated functional groups are appended to terminal positions of the polymer chain. These terminally poly-cationically active polymers may also be characterized by their ability to initiate the polymerization of tetrahydrofuran monomer at 25 C., as evidenced by an increase in the molecular weight of the polymer resulting from the attachment of recurring oxytetramethylene groups to each end of the original poly-cationically active polymer.

The substantially linear poly-cationically active polymers of this invention can be prepared by two general methods. The first method involves direct conversion of monomer to a di-cationically active polymer, using cer- Patented July 16, 1974 i tain catalysts as hereinafter defined. In a second method, preformed polymers in the 400 to 100,000 molecular weight range and having certain functional groupings are converted to poly-cationically active polymers, as hereinafter described. In general, the direct conversion process leads to the formation of an .essentially linear, dica'tionically active polymer, while the indirect conversion process can lead to the formation of either linear, di-cationically active or branched poly-cationically active polymers, depending upon the state of branching and terminal group functionality of the preformed polymer. By substantially linear polymer. is meant a relatively long chain polymer which may have substituent groups attached to the main polymer chain but suchsubstituent groups are generally of substantially lesser chain length than the main chain, normally less than half of the length of the main chain.

Direct Preparation of Di-cationically Active Polymers Certain acid polymerizable (i.e. cationically polymerizable) monomersmay beconverted directly to substantially linear di-cationically active polymers. T etrahydrofuran and .sym-trioxane are preferred monomers in this respect. Tetrahydrofuran provides a di-cationically active polyether having recurring oxytetramethylene groups and is particularly preferred. Di-cationically active polyether copolymers can be prepared, for example, from tetrahydrofuran or sym-trioxane and a minor amount (e.g..

less than 50 mole percent) of another acid polymerizableor copolymerizable cyclic ether (including cyclic thioethcr) ,e.g. propylene oxide, ethylene oxide, glycidyl meth- The, polymerization of tetrahydrofuran monomer alone.

or in admixture with another acid polymerizable cyclic'. ether monomer must be carried out in the presence of certain catalysts. These catalyst molecules can. conveniently be considered to consist of two components. Although.

some catalyst moleculesare dissociable, it should heappreciated that not all useful catalysts necessarily dissociate toany discernible degree. For example, it has been found that one mole of ,CF SO --O--O SCF a non-,

conductive compound suitable for use as catalyst, when also non-conductive) at room temperature produces a solution having high electrical conductivity. Accordingly, the" polymerization of tetrahydrofuran with or without additional cyclic ether monomer may be considered to be initiated by a heterolytic cleavage of the catalyst molecule to produce a first component which rapidly adds to the oxygen atom of tetrahydrofuran to form a complex cation and a second component or anion. Although the specific, mechanism of operation is not fully understood, it is believed that a hypothesis suggesting ionic components within the catalyst class is consistent with the wellknown cationic mechanism of tetrahydrofuran polymerization. Reference herein to the two components of the catalyst molecule is intended to identify those portions .50 added to about 10 moles of tetrahydrofuran (which is" of the -molecule which serve as the cation and anion donors, respectively, during the initiation of tetrahydrofuran polymerization.

A first class of useful catalysts can be represented by theformula DQ. Q corresponds to a radical which, in

anionic form, is a non-terminating anion in the polym-.

erization of tetrahydrofuran, i.e. it does not terminate the growing polytetramethylene oxide chain. The radical D corresponds to the residue remaining after deletion of a-hydroxyl group from a monobasic acid (hereinafter may be mixed with tetrahydrofuran (0.02 mol acid/ 1 mol tetrahydrofuran) and allowed to react at 2 5f C. A yield of polytetrahydrofuran greater than 50%- after one week indicates that the strong acid is a suitable catalyst parent,

acid.

The cationic polymerization of tetrahydrofuran using acid catalystshas been reported in theliterature, and ac-..

cordingly the evaluation of various monobasic acids for their utility in such polymerization need not be discussed in great detail Acids which are etfectivetetrahydrofuran polymerization catalysts include FSO H, CI SO H, HCIO H10 CF SO H, C F SO H, etc. and the corresponding D radicals derived therefrom are FSO ClSO ClO IO2, CF SO C F SO etc. Moreover the catalyst parent acid must be one ,which exhibits essentially no chain transfer activity in the polymerization of tetrahydrofuran. Accordingly chlorosulfonic acid is not a suitable catalyst parent acid because of itsability to transfer chloride ion to growing polytetrahydrofuran chains under normal conditions and to append chlorine chain terminating groups (See J. Furakawa and T. Saegusa Polymerization of'Aldehydes and Oxides, page 232, Interscience Publishers,, New York, 1963 As a result, ClSO is not a useful D component of the catalyst molecule when polymerization temperature in excess of about -10, C. are employed. At lower temperatures the chain transfer activit of catalysts containing ClSO radicals is suppressed to thepoint where such catalysts can ,be quite useful for producing substantially linear di-- cationically activepolyethers. Radicals preferred as D components includes FSO ClO and RfSO2 where R is a polyfiuoroaliphatic radical as hereinafter defined, e.g. CF SQ etc.

The Q component of this class of catalysts employed in thepreparation of di-cationically active polymers corresponds to a radicalwhich, in anionic form, is a nontermina'ting anion in the. polymerization of tetrahydrofuran, i.e. it does not terminate the, .polymerization of tetrahydrofuran, It has been well-established that, the heretofore known polymerization of tetrahydrofuran always involves a cationic mechanism, i.e. the growing polymer chain contains a single cationically activeend group, and the ability of the polymer to,add furthermonomerand increase in molecularweight depends upon the maintenance of a single cationically charged site. Many anions react with this charged site to bring about chain terminatio'n by a' charge neutralization reaction involving either,

a coupling reaction in which the anion (e.g. :Clf', Br-,

N031 .c 011 00 cn so e, etc.) combines .di-

rectly withthe. polyether cation to form an electrically neutral compound, or a transfer reaction inwhich a portion of the complex anion is transferred, usually as a halide ion, to formboth a neutral polyether molecule and alsoeither a neutral compound derived from the original. anion or a new anion of lower velectrical charge than the original anion. Examples .ofthe latter type are ClSO and the complexanions derived from relatively weak Lewis acids such as TiCL ZnI SiF and SeBr tion ensuessimultaneously at the opposite ends of the substantially linear growing polymer chain.

One particularly .-useful class of non-terminating anions,

or Q radicals are those derived from extermely strong protonic acids, sucl 1 as F C10; and R SO where R is a polyfiuoroaliphatic (including, polyfiuorocyclic aliphatic) radical containing from 1 to 18 carbon atoms and at least on fluorine substituent on the alpha carbon atom. R, may also contain hydrogen and other halogen atoms, such as chlorine, in addition to fluorine and may be interrupted by either oxygen or amine nitrogen atoms, provided such oxygen or nitrogen is vicinal to a fluorine substituted carbon atom. Preferably R, is at least half fluorinated, i.e. at least about half of the monovalent atoms appended to the carbon atoms of the R group are fluorine. For example, R; may be perfluoroalkyl (see US. 2,732,398), perfiuorocycloaliphatic, betahydroperfiuoroalkyl (see US. 2,403,207), omega-chloroperfiuoroalkyl (see U.S. 2,877,267), H(CX CX wherein two Xs attached to one carbon atom are fluorine and the remaining Xs are either hydrogen or a halogen (e.g. chlorine, fluorine), etc. Illustrative Rf groups include trifiuoromethyl, 2-hydro-hexafluoropropyl, pentafluoroethyl, 1,1-difluoroethy1, heptadecafluorooctyl, 1,1-difiuoro-2,2-dichloroethyl,

8-chloro-perfluorooctyl, etc.

Another class of useful non-terminating anions or Q radicals are the complexes derived from very strong Lewis acids, e.g. BF SbF SbCl AsF and PF Examples of such non-terminating anions are B134, SbF SbF (O SF)-, SbCl AsF and P1 A general method which can be used to determine whether a specific anion is terminating or non-terminating, as used herein, is to conduct the cationic polymerization of tetrahydrofuran in a conventional manner using a known acid catalyst, but with the addition to the polymerization system of a soluble salt containing that anion, thus investigating the effect of that anion on the polymerization reaction. For example, tetrahydrofuran monomer and a small amount (e.g. one mol percent of total monomer) of ethylene oxide can be polymerized by using 2 mole percent (based on total monomer) of borontrifluoride as the polymerization initiator under. temperature conditionscapable of providing of at least about 50% conversion of monomer to polymer, e.g. 20 C. If the same reaction is performed with the addition of 2 mole percent of a dissolved salt containing the anion in question, any significant decrease in the extent of conversion and/or in the molecular weight of the product formed demonstrates that the anion is a terminating species. Thus, lithium bromide, lithium nitrate, silver trifluoroacetate and silver cyanide cause reduction in conversions so that no more than 10% of polymer is produced, prov-,

ing that Br, N0 1 CF CO and CN- are terminating anions. On the other hand, when identical reactions are performed in the presence of silver perchlorate, silver trifluoromethane sulfonate, lithium hexafiuorophosphate and silver hexafluoroantimonate, no significant effects on either the amount of polyether produced or its molecular weight are noted, thus proving that C10 CF SO PF and SbF are non-terminating anions.

Anhydrides which are effective catalysts having the formula DQ include pyrosulfuryl fluoride, i.e. (FSO O (where FSO and FSO may be considered to be D and Q, respectively), (CF SO' O (CF SO and CF SO and C1 0, (ClO and C10 as well as their mixed anhydrides, such as FSO O'O SCF Salts which are effective catalysts for producing the di-cationically active polyethers of this invention include FSO F-PF CF SO F-SbF CF SO Cl-SbCl and ClO F-BF which may be considered to be FSO +PF CF SO +SbF CF3SO'2 'Sbc15 and C103+BF4 I'BSPEC- tively. Such salts may freqeuntly be most conveniently preparedby the direct reaction of the acid halide with the appropriate Lewis acid. A second catalyst class which is effective in producing the di-cationically active ethers of this invention by a direct conversion of monomers is the class of certain diesters of the abovernentioned catalyst parent acid, i.e. fluorosulfonic acid, polyfluoroaliphatic sulfonic acids (i.e.

R SO H) and perchloric acid, and a diprimary glycol.

This class may be represented by the formula DZCH (A) ,CH ZD,

where D is as defined earlier and. is preferably a fluorosultonate, polyfiuoroaliphatic sulfonate (e.g. R;SO

or perchlorate radical, A is a difunctional organic radical which is devoid of acetylenic and olefinic unsaturation and free of alkylatable groups containing Zerewitinoff hydrogen atoms (e.g. hydroxyl, amino, thiol and carboxylic acid groups), preferably an alkylene, oxyalkylene or recurring oxyalkylene radical, Z is oxygen or sulfur, and n is 0 or 1. Particularly preferred catalysts of this class are: 1,4-butane bis(fluorosulfonate), 1,4-butane bis- (trifluoromethane sulfonate) and the corresponding esters of poly(tetramethylene) glycol. These compounds are conveniently prepared by a direct method which involves the reaction of either pyrosulfuryl fluoride (fluorosulfonic anhydride) or trifiuoromethane sulfonic anhydride with tetrahydrofuran. When stoichiometric concentrations of either of these anhydrides and tetrahydrofuran are reacted at 30 C. to 0 C. the 1,4-butane diester is obtained in good yield. When excess tetrahydrofuran is used in this reaction, the resulting diester contains recurring oxytetramethylene groups and the average molecular weight of the product varies essentially directly with the molar excess of tetrahydrofuran employed.

Considerable latitude is permissible in the selection of conditions for the direct polymerization reaction. However, it is important that these reactions be conducted in a system which is relatively free of chain terminating agents. As used herein, the term chain termination connotes a chemical reaction during polymerization in which a cationically charged end of a polymer chain is effectively neutralized and a terminal group having essentially no further alkylatability under the conditions of polymerization is appended to the formerly cationically charged end portion of the polymer chain. Polymerization in accordance with this invention proceeds to give a product in which substantially all chain ends are cationically active. The presence of chain terminating agents (i.e. compounds which are only monoalkylatable under the selected reaction conditions, including soluble halide salts, acyl halides, alcohols, acids and anhydrides substantially weaker than fiuorosulfonic acid, etc.) which are alkylated by the cationically active ends of the polymer chain introduces a substantial number of inert end groups which prevent further chain propagation. It should be understood that some materials normally considered as chain terminating agents for polymerization reactions other than those described herein are not objectionable under some polymerization conditions in the present invention. In particular, polyalkylatable compounds, e.g. compounds having two or more active hydrogen atoms such as water, alkylene or polyalkylene ether glycols, ets. can react with two cationically charged polymer chain ends and thus can serve as chain extending agents. Water can react with a di-cationically active polymer to produce a mono-cationically active polymer with one hydroxyl group, and the hydroxyl group of this product can be readily alkylated by another di-cationically active polymer to form a new di-cationically active polymer of increased chain length. This tolerance to water in the polymerization system of this invention is very advantageous from an economic standpoint. Accordingly, polyalkylatable compounds, in amounts up to about stoichiometric equivalence with the catalyst concentration, are not necessarily objectionable in the preparation of dicationically active polymers.

Although the use of a solvent is often not essential; an inert solvent may be desirable to moderate the rate of reaction or to permit easier handling of the reaction mixture. Suitable solvents include methylene chloride, fluorohalocarbons, cycloalkanes (e.g. cyclohexane), etc. The

40 C. to +70 C. when tetrahydrofuran is employed, although temperatures up to about 100 C. can be used with other monomers, such as sym-trioxane. When solvents are employed it is normally desirable to conduct the reactions at lower temperatures, e.g. 20 C. to +40 C., and to maintain solvent concentration below about 40% by weight.

Themolecular weight of the resulting polymers can vary over wide limits, e.g. from about 400 to 1,000,000 and higher. An effective method for controlling the molecular weight is provided by regulating the molar concentration ratio of catalyst to monomer. When higher molecular weights are desired, the above mol ratio is preferably between about 0.001 and 0.01, the lower molecular weights generally being obtained with a mol ratio between about 0.01 and 0.5.

Indirect Preparation of Terminally Poly-cationically Active Polymers Although the direct method of preparation of the dicationically active polymers of this invention is extremely useful, it is generally limited to certain cationically polymerizable monomers, as explained previously. Considerable versatility is provided by an indirect method of preparing a terminally poly-cationically active polymer which utilizes as a starting material a preformed polymer (i.e. prepolymer) which has certain functional substituents only in terminal positions and which is otherwise free of alkylatable groupings (e.g. olefin, amine, hydroxyl, thiol, carboxylic acid, etc.). Appropriate prepolymers can be classitied in two categories:

I. Polymers containing -OH or SH (or the alkali metal salts thereof), COOH or SO H terminal groups can be converted to terminally poly-cationically active polymers by reaction with either a non-terminating catalyst parent acid, or certain derivatives thereof as specified below, wherein the catalyst parent acid is capable of initiating the cationic polymerization of tetrahydrofuran per se. Specifically, the terminally poly-cationically active polymers may be prepared by reacting the abovementioned prepolymer with a catalyst parent acid, its anhydride, its acyl halide or an alkylene biester of the structure where D, Z and A are as hereinabove defined. Illustrative of these catalyst parent acids and their derivatives are FSO H, (FSO O, FSO C H O SF, CF SO H,

) 20, (C HgO 2O2SCF3,

HClO

C1 ClO --C H --O- Cl, etc. These conversion reactions to form the terminally poly-cationically active polymers are condensation reactions in which either a salt, water, a hydrogen halide or an acid (i.e. catalyst parent acid or the derivative) is produced as a by-product, depending upon the derivative used to convert the prepolymer to its cationically active state. Such condensation reactions are accomplished in a manner well known in the field of polymer modification. It is often desirable to employ a dehydrating agent or an acid acceptor in the reaction, usually in stoichiometric amount, or as a solid heterogeneous phase, to inactivate the by-product. The resulting terminally poly-cationically active polymers may be considered to be polyesters, polythioesters or polymixed anhydrides. They are characterized by their ability to initiate tetrahydrofuran polymerization, thereby forming block copolymers, as well as by their remarkable alkylating or acylating ability. The terminally polycationically active polymeric products derived from polymeric polyols and polythiols (or the corresponding alkali metal salts) are excellent alkylating agents, as are also the products formed by the reaction of the abovementioned alkylene biesters with polymeric polycarboxylic or polysulfonic acids. The terminally poly-cationically active polymers de rived from the reaction of polymeric polycarboxylic acids,

and anhydrides or their acyl halides are mixed anhydrides which possess remarkable activity as acylating agents.

II. Polymers containing acyl (i.e. carbonyl or sulfonyl) halide terminal groups, preferably acyl chloride or acyl bromide end groups, may be converted to polymeric mixed anhydrides by reaction with a non-terminating acid (i.e. catalyst parent acid) capable of initiating the polymerization of tetrahydrofuran, or a salt thereof, preferably a silver salt thereof. Illustrative reactants for the preparation of terminally poly-cationically active polymers forrn the abovementioned prepolymers include FSOgAg, CF SO H, CF SO Ag, HClO and AgClO Prepolymer reactants having two or more terminal reactive groups which are suitable for the preparation of cationically active polymeric compounds by the indirect process can be provided by various means. Polymers containing terminal hydroxyl groups are well known. Several polyethers containing two terminal hydroxyl groups are readily available commercial materials, including polyethers derived from ethylene oxide, propylene oxide and tetrahydrofuran in a variety of molecular weights. ,Polyoxymethylene polymers containing hydroxyl end groups are also obtained from the ionic polymerization of formaldehyde or sym-trioxane. Branched chain polyethers containing more than" two terminal hydroxyl groups may be prepared by polymerizing ethylene oxide in the presence of a basic catalyst and a polyol containing more than two hydroxyl groups. Thus, the use of trimethylolpropane or pentaerythritol as a reactant in ethylene oxide polymerization produces a branched polyether containing three of four terminal hydroxyl groups, respectively. When such branched materials are utilized as the prepolymer, the resulting products have a terminal cationic activity greater than 2.

Polyesters containing hydroxyl end groups have been prepared by using an excess of polyol monomer in the condensation reaction with a dicarboxylic acid. The molecular weights of such polyesters are controlled by regu. lating the degree of conversion of the monomers and the excess of polyol employed.

Hydroxyl terminated vinyl polymers derived fromethylenically unsaturated monomers have been prepared by the use of a suitablefree radical initiator, such as hydrogen peroxide.

Methods for the preparation of thiol terminated polymers are also known. Thiol terminated polymers may be prepared by the addition of a slight excess of hydrogen sulfide or alkylene dithiols to alkylene bisesters of acrylic and methacrylic acid. A second process for providing dithiol terminated polymers involves the condensation of certain organic dihalides with a, slight excess of sodium sulfide or polysulfide. Still another process for preparing thiol. terminated polymers involves the esterification of carboxyl terminated polymers with mercaptoethanol.

Polyesters or poly-N-alkyl amides containing terminal carboxylic acid (or sultonic acid) groups can be made by condensing a slight excess of an appropriate dicarboxylic acid (or disulfonic acid) with a polyol or polysecondary amine, respectively. Monomers which are capable of polymerizing on treatment with a dilithio-organic compound (e.g. styrene polymerized using 1,2-diphenyl-1,2-dilithioethane as catalyst) yield polymeric dicarboxylic acids or disulfonic acids on treatment with carbon dioxide or with sulfur dioxide and an oxidizing agent, respectively.

Acyl halide terminal groups (i.e. carbonyl and sulfonyl I halide groups) on polymers may be provided by various means. In one case, polymers containing free acid groups may be converted to the desired prepolymer derivatives by reaction with phosphorus pentachloride or thionyl chloride or bromide. The use of a slight excess of an alkyl-' ene or arylene diacyl chloride (e.g. adipyl chloride,terepht-halyl chloride or p,p-diphenyl disulfonyl chloride) provides an opportunity for making polyesters or polyarnides containing terminal acyl, e.g. sulfonyl halide groups. The reaction of excess phosgene with polymers containing alcohol groups alfords still another method of introducing terminal acyl halide groups into the prepolymer, in this case chloroformate groups.

Normally wide latitude is available in the selection of reaction conditions to be employed in the indirect process for preparing the cationically active polymers. When uncrosslinked, terminally soluble poly-cationically active polymers are desired, e.g. for reactive intermediates for subsequent chemical modification, it is normally desirable to employ a prepolymer having a molecular weight of about 400 to 20,000 and containing the requisite functional groups in terminal positions on a linear or branched chain. The use of an approximately one to five-fold stoichiometric concentration of catalyst parent acid or derivative thereof to react with said functional groups is normally preferred for the preparation of an uncrosslinked product. When an acid acceptor is desired, the prepolymer may first be mixed with a tertiary amine, e.g. triethylamine, in a concentration which is just sufficient to neutralize the acid formed by the reaction (when a prepolymer containing terminal alkali metal alkoxide or mercaptide groups is employed, it is usually unnecessary to use any additional acid acceptor). Selection of reaction temperature is normally not critical, and a preferred range of 80 C. to 100 C. may be employed, although the reaction rate at the lower temperatures may be undesirably slow. Inert, anhydrous solvents are frequently used in this indirect process, and suitable solvents have already been discussed.

The preformed polymeric reactant may contain situated along the chain various groups other than as specified above, provided these are inert to the action of the catalyst parent acid derivative used in the reaction and to the alkylation or acylating activity of the resulting poly-cationically active polymer. Thus, groups such as ester, ether, nitro and halo can be present in the polymer without interfering with the preparation of poly-cationically active polymers made by the indirect process.

From the foregoing description it is evident that a great number of preformed polymers containing suitable terminal functional groups can be used to prepare the cationically active polymers of this invention, including such suitable preformed polymers as polymeric materials based on styrene, vinyl chloride, vinyl alkyl ethers, esters of acrylic and methacrylic acid, vinyl esters, and polymers such as polyesters, polyethers, etc.

Reactions of Poly-cationically Active Polymers As mentioned earlier, the poly-cationically active poly mers of this invention are remarkably effective alkylating or acylating agents and, indeed, may be characterized by their alkylating or acylating ability. In addition, they serve as effective polymeric initiators for the further polymerization of acid polymerizable monomers, the prod nets of which are block copolymers. Many other useful products can be derived from these poly-cationically active polymers as intermediates, taking advantage of the strongly electrophilic nature of these macromolecules.

Inorganic and organic compounds (including polymeric materials) containing active hydrogen, particularly compounds with OH,

SH, -SO H, and -NHR groups (R' is hydrogen, alkyl or aryl), readily react with the poly-cationically ac tive polymers of this invention, these reactions being essentially alkylation or acylation reactions in which the polymer chain alkylates or acylates the electronegative group ,to which the active hydrogen is attached. Suitable active hydrogen containing compounds include water, hydrogen sulfide, ammonia, urea, hydrozine, aniline, methyl amine, mercaptoethanol, glycolic acid, polymers of acrylic "acid, vinyl alcohol polymers, succinic acid, glycine, proteins, piperazine, triethylene tetramine, ethylene glycol,

etc. The products of this alkylation or acylation reaction are thus the corresponding polymeric derivative and the catalyst parent acid. In many cases an acid acceptor isdesirable to neutralize the strong catalyst parent acid product of the reaction. This neutralization is frequently necessary to avoid undesirable side reactions. In the alkylation or acylation of amino compounds, including amines and ammonia, an excess of amino compound may be used to neutralize the acid product. In instances where the reaction is rapid, e.g. the alkylation of an alkyl mercaptan, and acid acceptor such as pyridine can be used to advantage, preferably in stoichiometric amounts.

Reaction temperatures are generally not critical, and a range between about C. to C. has been found to be suitable, although the lower temperaturesteg. below 25 C.) are generally preferred to moderate the rate of reaction. The use of an inert solvent is not always necessary and is, in some cases, undesirable. Suitable inert solvents have been discussed earlier. Control of reactant concentrations is important in alkylation and acylation reactions employing the cationically active polymers. The functionality of the reactants, the requirement of an acid acceptor and the desired end product should be considered in determining the optimum proportion of reactants, as will be apparent to those skilled in this art. The function ality of the compound to be alkylated or acylated is equivalent to the number of alkylatable or acylatable groups present in the molecule multiplied by the number of times that group can react with the cationically active sites on the polymer of this invention. For example, water has a functionality of two, since each water molecule is capable of reacting with two cationically active sites on the polymer. If water reacts with one cationically active site on the poly-cationic polymer, the product is a polymeric polyol; if the water reacts With two cationically active sites, the product is a polymeric polyether. Similarly, ammonia having a functionality of four can react with the polycationically active polymeric alkylating agent to produce a polymeric primary, secondary or tertiary amine, or a quaternary ammonium salt. If the polymeric primary amine is desired, therefore, a large excess of ammonia is preferably used, e.g. at least a five-fold stoichiometric excess.

The following is intended to clarify further theimportant effects of reactant functionalities and concentrations on the nature of the reaction products. If a compound having two active hydrogen atoms is reacted with a po l ymer containing two cationically active groups, the product is a chain extended linear polymer when the molar concentration ratio of the reactants is close to unity. When the compound containing two active hydrogen atoms is used in excess, preferably at least a two-fold stoichiometric excess, thenthe di-substituted polymeric product retaining functional groups is favored, and this technique provides a means for preparing low molecular weight polymeric dithiols or dicarboxylic acids using excess alkylene dithiols (or H 8) or dicarboxylic acids, respectively. If a compound having three or more active hydrogen atoms is reacted with the di-cationically active polymer having two cationically active groups in approxi: mately stoichiometric proportion, the principal product is a crosslinked polymer, the properties of whichcan be varied by appropriate selection of the reactants.

With a poly-cationically active polymer having more than two cationically active groups in terminal positions of a branched chain, the product of reaction with a com pound having a single active hydrogen is a simple replacement product, while the product of its reaction with a compound having two or more active hydrogen atoms may provide a crosslinked polymer.

The polycati0nically active polymers of this invention also react with numerous metal salts (e.g. potassium cyanate, sodium phenolate, etc.) to effect a double decomposition reaction the products being the polymer resulting from the alkylation of the salt anion by the cationically active polymer and the salt of the catalyst parent acid. Salts of alkali metals, e.g. lithium iodide, sodium cyanide, potassium cyanate, sodium bisulfide, sodium bisulfite, sodium hydroxide, monosodium adipate, disodium succinate, potassium acid phthalate, sodium phenoxide, etc. are preferred, particularly when very soluble in the reaction medium, although salts such as calcium hydroxide and silver cyanide can also be used. Such reactions may be conducted either in homogeneous solutions or in heterogeneous dispersions. These reactions are one preferred method for obtaining the desired derivative of the cationically active polymer, since the catalyst parent acid is not generated and an acid acceptor is not needed.

The above reaction of the poly-cationically active polymers of this invention with metallic salts is similar to the alkylation of compounds containing active hydrogen, discussed earlier, in that effects of reactant functionalities and concentrations on product structure apply here as well. Frequently one may use alternate processes for the preparation of the desired polyfunctionally terminated polymers. Thus one may prepare polytetramethyleneoxide containing, primary amine end groups by use of any of the following methods: (A) Reaction of the di-cationically active polymer of tetrahydrofuran with excess ammonia as described previously; (B) Reaction with lithium azide followed by reduction of the resultant azide groups to the primary amines; (C) Reaction with lithium cyanide followed by hydrogenation of the terminal nitrile groups to primary amines; (D) Reaction with p-nitro sodium phenoxide followed by hydrogenation of the nitro groups to primary amines; (E) Reaction with lithium phthalimide followed by a subsequent reaction of the resultant imide groups with hydrazine to give the desired primary amines. Certain of these reactions can occasionally be used to great advantage when it is desired to avoid side reactions, e.g; polyalkylation which would occur normally to some small extent in the reaction of the poly-cationically active polymer with a compound containing several active hydrogens, e.g. ammonia. Thus if one desires a polymer containing amine groups only in the form of terminal primary amines, the lithium azide and phthalimide reactions shown above (B and E, respectivley) will generally give better results than the reaction of the poly-cationically active polymer with ammonia.

The poly-cationically active polymers of this invention also react with those aromatic compounds capable of undergoing a Friedel-Crafts reaction to give the ring alkylated or acylated derivative. Benzene and many of its derivatives undergo this reaction. The ring alkylation of benzene: is essentially complete in about 4 hours at 78C.- If. electron-donating groups (e.g. alkyl, alkoxy, hydroxyl) are present on the ring, the reaction is' greatly accelerated and the alkylation occurs primarily in the orthoand para-ring positions. On the other hand, if electron-withdrawing groups (eg halo, nitro, trifluoromethyl) are present on the ring, the reaction is noticeably slowed. Indeed, p-dichlorobenzene, nitrobenzene and benzotrifluoride are sufficiently unreactive to be used as inert solvents for the reaction.

The alkylation and acylation of aromatic compounds which are capable of. undergoing a Friedel-Crafts reaction using these poly-cationically active polymers leads to extremely valuable products and intermediates for chemical synthesis. Such aromatic compounds include benzene, toluene, mesitylene, ethyl benzene, phenol, anisole, napthalene, fiuorene, acenapthene, diphenyl, diphenyl ether, anthracene, dibenzofuran, etc. The introduction of aromatic groups onto the polymer chain provides an opportunity for subsequent chemical modification of the polymer, such as by chlorination, nitration, sulfonylation, polyetherific ation, and polyesterification reactions. In the alkylation of phenol it is noteworthy that the phenolic hydroxyl group appears to be much less subject to alkyl- 12 ation under acid conditions than the para-ring position, which is activated by the phenolic hydroxyl.

Compositions of matter based on aromatic compounds, particularly phenolic compounds, which have been alkylated or acylated with the cationically active polymers of this invention may be used to obtain flexible resins, e.g. phenolic resins, epoxy resins, polycarbonate resins, aminoaldehyde resins, etc. Such alkylated or acylated phenolic materials can also be used as intermediates in the organic syntheses of dyes, drugs, and other chemical compounds.

The poly-cationically active polymeric alkylating agents of this invention also alkylate by addition to compounds having localized electron-rich sites. This alkylation by addition is illustrated by their reaction with tertiary amines to yield the quaternary ammonium 'saltof the parent catalyst acid.

It is significant to note that in most of the foregoing description it is not necessary to prepare and isolate the poly-cationically active polymers of this invention. as separate and distinct steps. Frequently the poly-cationically active polymers of this invention are intermediates in the preparation of high molecular weight polymers which are valuable per se, as is true in the preparation of polytetramethylene oxide from tetrahydrofuran. The use of the catalysts of this invention affords a very simple and economical means for preparing this extremely useful polymer from the monomer. However, the cationically active polymers most often find use as intermediates in graft or block copolymerization or in alkylation or acylation reactions, as already described. Where this is the case, it is frequently desirable to prepare the polycationically active polymer in situ and carry out the desired alkylating or acylating reactions either simultaneously with, or subsequent to, its formation.

The novel products and processes described herein find utility as useful materials in the preparation of plastic and protective coating compositions, elastomers, polymeric surface active agents, impregnants, binders, potting com-. positions, adhesives, fibers, tape backings, foams and films.

The following examples will illustrate the invention.

Example 1 This example illustrates two extremely useful processes for making high molecular weight polytetramethylene oxide.

A. 444 grams of anhydrous tetrahydrofuran was placed in a round bottom flask equipped with a stirrer and cooled to about 30 C. in a Dry Ice bath before adding 0.9 gram of (CF SO O. The mixture was allowed to warm with stirring to room temperature, and a continuous increase in viscosity was noted at this temperature. After several hours, the solution was too viscous to stir. The reactants were allowed to stand above 72 hours at room temperature. The di-cationically active product, then a non-flowing rubbery mass, was cut into small pieces and these were quenched in dilute aqueous NaOH overnight. Then, after being washed with water, the polymer was dissolved in tetrahydrofuran and reprecipitated in water. The yield of dried, off-white polymer was 336 grams, a conversion of nearly 76%. The molecularweight of the product was approximately 300,000 as estimated from the inherent viscosity of 2.48 in benzene at 25 C. In the unvulcanized state the polymer had a tensile strength of 5470 p.s.i. and an ultimate elongation of 650%. Low temperature properties were excellent, with a brittle point below R0 C. This polyether was vulcanized using both a normal peroxide-sulfur, and a peroxide-divinyl benzene recipe to yield very tough, resilient elastomer with excellent water resistance. The unvulcanized product may be used in protective coatings, paint formulations, etc.

B. One liter of tetrahydrofuran was distilled from LiAlH, into a two liter flask equipped with a stirrer. 0.5 ml. of pyrosulfuryl fluoride was added at room temperature. After stirring for a short period to homogenize the reactants, agitation was stopped and the materials were allowed to stand overnight. At the end of this time the reactants had been converted into a non-flowing, colorless mass which, except for a slight increase in rigidity, underwent no observable changes for five days. The polymer was then cut into pieces, quenched in dilute aqueous ammonia, dissolved in tetrahydrofuran, reprecipitated in water and dried. The resulting polymer was a hard, white, leathery material which had an inherent viscosity of 5.11 in benzene at 31.5 C. The product yield was 75 percent, and the calculated molecular weight was about 700,000. Coatings prepared from this high molecular Weight polymer were very tough and abrasion resistant.

Example 2 This example describes several reactions in which dicationically active polymers were used to alkylate ammonia and various primary amines.

A. 275 ml. of anhydrous tetrahydrofuran was placed in a 500 ml. round bottom flask equipped with a stirrer. The flask was cooled to about -40 C. and 3 ml. of trifluoromethane sulfonic anhydride was added. On warming to room temperature an increase in viscosity was noted indicating that polymerization was taking place. When the solution was fairly viscous, ammonia gas was bubbled slowly through the solution of the di-cationically active polyether to maintain a relatively low concentration of ammonia. When the addition began there was an immediate reaction, as evidenced by a very rapid and abrupt viscosity increase of the solution. Ammonia addition was stopped when the reactants could no longer be satisfactorily stirred. The product was poured into dilute aqueous sodium hydroxide and heated with agitation on the steam bath. It was then washed with water and dried in a vacuum oven at 50 C.

The product (150 g.) was not completely soluble in benzene, whereas normal tetramethylene oxide polymer is completely soluble in benzene. It was soluble in methyl ethyl ketone, in which solvent it had an inherent viscosity of 0.402 corresponding to an approximate average molecular weight of 28,000. Elemental analysis gave 2.22% N, which corresponds to about 44 nitrogen atoms per viscosity average molecule. This branched chain polyether-polyamine product was curable to a very tough rubber having good adhesion to aluminum when heated with 1% by weight of the diglycidyl ether of bisphenol-A.

B. 417 g. of tetrahydrofuran and 83 g. of propylene oxide were placed in a 1 liter flask equipped with stirrer and drying tube. The reactants were cooled to -20 C. and 26 ml. of (CF SO O was added as catalyst. Cooling was discontinued and the reactants were stirred for 20 minutes. After this period a viscous solution of the dicationically active copolymer was obtained. Polymerization was terminated by pouring the reactants into a mixture of 300 ml. of liquid NH and 250 ml. of tetrahydro- 'furan maintained at -70 C. Volatile materials were then removed and the polymer was washed with dilute aqueous KOH to remove the catalyst residues. The final w,w'-C0- polyether diprimary diamine (200 g. yield) was a liquid at room temperature. Analysis of this material gave the following results: molecular weight=2637, percent nitrogen=1.16 (corresponding to 2.18 Ns/molecule), total amines per molecule by perchloric acid titration:

This copolyether diprimary diamine was cured by re action with the diglycidyl ether of bisphenOl-A. A rubbery vulcanizate was obtained which stitfened much more slowly with decreasing temperature than a comparable material made from a diprimary diamine of the homopolymer of tetrahydrofuran.

C. 550 ml. of tetrahydrofuran was placed in a 1 liter flask equipped with stirrer and drying tube. 25 ml. of trifluoromethane sulfonic anhydride was added at room temperature with vigorous stirring and cold water cooling. About 4 minutes after the beginning of catalyst addition cooling was discontinued, and the somewhat viscous solution of the di-cationically active polymer was poured into a stirred mixture of about 500 ml. of liquid ammonia in 500 ml. of tetrahydrofuran maintained at about 70 C. Addition required about 2 minutes. The total reactant mass at this point was a cloudy white liquid. It was stirred for a short time at 70 C., and then allowed to warm to room temperature overnight. Thepolyether diprimary diamine formed was reprecipitated in water and washed repeatedly with aqueous base and water, then dried in vacuo at 60 C. The yield was 199.8 g. Analysis of the low melting wax product gave the following results: 0.904% nitrogen; number average molecular weight 3350, hence about 2.16 amine groups per molecule.

D. 125 ml. of tetrahydrofuran and 6 ml. of trifiuoromethane sulfonic anhydride were charged to a 250 ml. flask equipped with stirrer and drying tube. Four minutes after the catalyst addition the reactants had exhibited an exotherm and become somewhat viscous. ml. of isobutyl amine was added rapidly to the di-cationically active product at this point, and the reactants were agitated overnight. The product was then reprecipitated in water, washed with hot aqueous potassium hydroxide and then washed with hot water until the wash water was neutral. The material was then dried several days in a vacuum oven at 60 C. Yield=55 grams. Analysis gave: 1.23% nitrogen and a number average molecular weight of 2180; hence 1.91 nitrogen atom per molecule in the form of secondary amine groups.

Such polymeric diamines are useful for block copolym erization (e.g. condensation with a carboxyl-terminated polyester or polyamide). They also undergo chain extension and crosslinking reaction upon treatment with diisocyanates, epoxy resins, dia ziridine compounds, various aminoplast resins (e.g. tetramethylol urea), etc. Products derived from polyether diamines have excellent water resistances, toughness and abrasion resistance and find great utility in the protective coating field.

E. 2500 grams of tetrahydrofuran was distilled and condensed into a 5 liter flask through a column packed with molecular sieve material. The flask was equipped with a stirrer and drying tube. The tetrahydrofuran was cooled to 62 C. and 425 grams of (CF SO O was added. The reactants were allowed to warm to 0 C. and maintained at that temperature for 15 minutes. The viscous solution of the di-cationically active polymer was rapidly poured into a stirred mixture of 858 grams of allyl amine and 500 ml. of methylene chloride maintained at 70 C. The combined solutions were allowed to Warm to room temperature, and the volatile components were then removed. Upon dilution with benzene a significant quantity or precipitate formed, the precipitate having the formula 9 C aS NH3CH2CH=CH2.

The precipitate was removed by filtration and could be used to recover the original catalyst. The benzene solution was then treated with a strongly basic ion exchange-resin to remove the remaining traces of catalyst. After removal of solvent the polymer analyzed as follows: number average molecular weight=2800, secondary amine equivalent=1390 (indicating 2.01 secondary amine groups per molecule), 1.27% N (indicating 2.58 nitrogen atoms per molecule).

F. 500 ml. of anhydrous tetrahydrofuran was placed in a one liter flask equipped with a stirrer and drying tube. The flask was cooled to -70 C.., and 20 ml. of pyrosulfuryl fluoride was added. The reactants were allowed to warm to 0 C. and were maintained at that temperature for 10 to 12 minutes. The viscous solution, of the dicationically active polyether was poured rapidly into a stirred flask containing 300 ml. of ethyl amine at -70 C. After being allowed to warm overnight to room temperature with stirring the unreacted volatile materials were removed. Catalyst residues were removed by treatment with potassium hydroxide in methanol, followed by treatment in benzene solution with a strongly basic ion exchange resin. After drying, 165 grams of amine terminated polyether, identified as N,N'-diethyl poly-(tetramethylene oxide) diamine, was obtained. The number average molecular weight was 1550. Analysis: 1.77% N (indicating 1.96

nitrogen atoms per molecule) and 1.32 milliequivalents/ gram of amine (indicating 2.05 amine groups per molecule).

G. 400 ml. of anhydrous tetrahydrofuran was placed in amine at a temperature of 70 C. Catalyst residues were then removed by filtration and treatment with a basic ion exchange resin. The yield of purified polyether di-secondary amine was 110 grams. The number average molecular Weight was 2700. Analysis: 1.09% N (indicating 2.1 nitrogen atoms per molecule), 1410 amine equivalent weight (indicating 1.9 amine groups per molecule). This diamine product may be used to cure epoxy resins to a hard, very impact resistant state.

The following materials were placed in a 500 ml. flask equipped with a stirrer: 15.5 grams of this polyether disecondary diamine, 1.14 grams of trans-2,5-dimethyl piperazine, and 207 grams of dimethyl formamide. 4.8 grams ,of methylene-bis-(4-phenylisocyanate) in a solvent mixture consisting of 33 grams of dimethyl formamide and 66 grams of xylene was added dropwise to the stirred amine solution at room temperature. A significant viscosity increase was observed. Films were cast from this solution after completion of the chain extension reaction. The resulting snappy elastomer had a tensile strength of 4060 pounds per square inch at 525% ultimate elongation. Elastic fibers having good properties may be wet spun from a 15% solution of this product in dimethyl formamide.

Example 3 This example shows the preparation of di-cationically active polyether and its use in preparing the corresponding polyether dithiol and products derived therefrom.

20 ml. of purified tetrahydrofuran was placed in a 250 ml. round bottom flask equipped with stirrer. At about 40 C. 3 ml. of trifluoromethane sulfonic anhydride was added, and the reactants were allowed to warm to room temperature and polymerize with stirring. Within about one hour a thick paste had formed; To this dicationicallyactive polymer was added 100 ml. of anhydrous pyridine saturated with hydrogen sulfide, and with 'to an approximate molecular weight of 100,000. Elemental analysis gave 0.46% S, corresponding to 14 sulfur atoms per moleclule. Some chain extension had occurred via the formation of thioether linkages and the terminal groups were thiols. Chain extension and the accompanying molecular weight increase may be minimized by quenching the tetrahydrofuran polymer in liquid hydrogen sulfide.

Such polymeric dithiols, including polysulfide thiols, are

readily cured by reaction with ethylenically diunsaturated compounds (e.g. ethylene dimethacrylate), active polyhalides (e.g. ethylene dibromide; 1,2,3-tribromopropane), -poly-isocyanates and certain oxidizing agents such as barium peroxide. Block copolymers are produced by the free .radical polymerization of ethylenically unsaturated monothem in the presence of the polymeric dithiols. The latter reaction is illustrated below.

Using the polyether dithiol made above, the following charges were made in ampoules:

(1) 9.5 g. styrene 0.5 g. polyether dithol 20 g. benzene 30 mg. azobisisobutyronitrile 7.5 g. styrene 2.5 g. polyether dithiol 20 g. benzene 30 mg. azobisisobutyronitrile 5 g. styrene 5 g. polyether dithiol 30 g. benzene 30 mg. azobisisobutyronitrile 10 g. styrene 20 g. benzene 30 mg. azobisisobutyronitrile These ampoules were agitated at 50 C. for 5 days. The resulting block copolymers and the homopolymer control were reprecipitated in heptane and dried. Yields: (1) 6.2 g. (2) 4.8g, (3) 6.7 g., and (4) 4.6 g. Infrared spectra were obtained, and these showed the presence of both poly-styrene and polyether units in the products of ampoules 1, 2 and 3, with the proportion of polyether increasing in that order. Ten weight perecnt solutions of each homopolymer in benzene were mixed, and two distinct liquid phases formed in the mixture on standing for a few hours. No such phasing was observed for 10% solutions in benzene of the block copolymeric products 1, 2 and 3 above, even after much longer periods of time. The flexibility and impact strength of the block copolymer increases appreciably with increasing polyether content. Such block copolymers find use incoatings, binders, adhesives and the manufacture of plastic parts.

Example 4 This example shows the preparation of a di-cationically active polyether and its use in preparing a polyether dicarboxylic acid.

ml. of anhydrous tetrahydrofuran and 10 ml. of freshly distilled trifluoromethane sulfonic anhydride were placed at room temperature in a 250 ml. flask equipped with a stirrer and drying tube. The reaction was exothermic and a cold water bath was used to modify the exotherm. After a few minutes the reaction mixture became quite Viscous, and 100 ml. of tetrahydrofuran containing 20 g. of succinic acid as a slurrry was added to the di-cationically active polyether. The solution was agitated at room temperature for several hours and then poured into dilute aqueous ammonium hydroxide, which produced a cloudy solution but no coagulation. Addition of a small amount of concentrated I-ICl precipitated the polymer. The polymer was then washed with water and twice reprecipitated from tetrahydrofuran into water. The

' product was then washed four times with hot water and dried in the vacuum oven at 50 C. Yield: 49 g. Analysis: Number average molcular weight=3300; carboxyl neutralization equivalent-=l640. This data gives 2.01 COOH groups per molecule of polymer in which the terminal carboxylic acid groups are attached to the polyether chain through ester linkages. The brittle waxy product was quite surface active in aqueous alkaline solutions. It may be used to form block copolymers by condensation with hydroxyl-terminated polyethers or polyesters or with amine terminated polyamides. It may also be cured to a rubbery state by reaction with polyepoxides or polyaziridines.

Example This example illustrates the use of di-cationically active polyethers prepared by the direct method to initiate a subsequent polymerization, thereby producing block copolymers.

A. ml. of tetrahydrofuran and 0.5 ml. of trifluoromethane sulfonic anhydride were sealed into a glass ampoule. After room temperature agitation overnight, the product containing a di-cationically active polymer of tetrahydrofuran was non-flowing. The ampoule was opened, cooled in liquid air and 10 ml. of ethylene oxide was then added, and the ampoule was rescaled. After vigorous overnight shaking at room temperature a ho mogeneous clear solution resulted. Then during mild agitation for several days the viscosity was observed to increase. Agitation was continued until the reactants suddenly turned black. The product was then immediately quenched in dilute aqueous sodium hydroxide for 70 hours, and then washed with water (containing some sodium bromide to prevent dissolution of the polymer).

' After drying at 50 C. overnight in a vacuum oven, a viscous liquid, dark red polymer (7 g.) was obtained. Its block copolymeric nature was indicated by infrared analysis and also by the surface activity of the product and the fact that it exhibited a cloud point in water. Stable emulsions of benzene in water could be produced by shaking benzene in a 1% aqueous solution of the product.

B. 10 ml. of tetrahydrofuran and 0.5 ml. of trifluoromethane sulfonic anhydride were allowed to react in a glass ampoule at 25 C. After 24 hours the ampoule was opened and 10 ml. of distilled styrene was added to the solid reaction product. The ampoule was rescaled and vigorously shaken for 72 hours. At this point the reactants were in the form of a clear, homogeneous, viscous solution. The material was then quenched in dilute ammonium hydroxide for 24 hours.

The dried polymer (9 g.) was a low melting solid. Infrared spectroscopy clearly indicated the presence of units of both monomers, and no OH absorption. Clear films were cast from a solution of this block copolymeric product.

Example 6 This example illustrates the use of di-cationically active polymers in the alkylation of anions of appropriate salts.

A. 330 grams of anhydrous tetrahydrofuran was placed in a 3 neck flask with stirrer. The flask and charge were cooled in an ice bath, and 47.4 grams of trifiuoromethane sulfonic anhydride was added. After the initial exotherm was dissipated the ice bath was removed. After about 45 minutes the reactants had become noticeably more viscous. At this point a solution of 70 g. of sodium phenoxide in 500 ml. tetrahydrofuran was added.

The resulting polymer was coagulated in water, washed a number of times with hot ammonium hydroxide and then with hot Water. The polymer was dried 24 hours at 80 C. in a vacuum oven. The number average molecular weight of the polyether was 974. Yield=223 g. Infrared analysis confirmed the presence of phenoxy groups, and showed no absorption for free phenol or OH. When heated in air to 310 C. at a constant rate of 10 per minute, only a 10% weight loss was observed, indicating the outstanding thermalstability of the di-phenoxy terminated polytetramethylene oxide.

B. 100 ml. of anhydrous tetrahydrofuran was placed in a 250 ml. round bottom flask equipped with a stirrer and drying tube. Ten milliliters of trifluoromethane sul fonic anhydride was added at room temperature. An exotherm and viscosity increase were noted. A few minutes after anhydride addition 26 g. of potassium cyanate was added to the di-cationically active polymer. Vigorous stirring was maintained at room temperature over a Weekend. During the latter part of this period, however,

13 the reactants gelled. The product was then shaken with benzene, and a soluble and an insoluble portion were found. Both portions exhibited fairly strong alkyl isocyanate absorption bands in the infrared (4.4 microns; potassium cyanate absorbs at 4.6 microns). The soluble material was rendered insoluble by almost instantaneous reaction at 25 C. with hexamethylene diamine, and the resulting insoluble material showed no isocyanate absorption in the infrared, indicating complete formation of the urea.

Example 7 This example describes the use of a diester catalyst which is effective in the preparation of di-cationically active polymers.

8 milliliters of trifluoromethane sulfonic acid anhydride was charged to a test tube and cooled to 60 C. 4 ml. of tetrahydrofuran was then added dropwise over a five minute period. A solid formed immediately. The temperature was allowed to rise to 0 C. and 25 ml. of cold carbon tetrachloride was added. After thorough mixing, the liquid was decanted and discarded. The solid remaining was dissolved in 150 m1. of boiling carbon tetrachloride and recrystallized by cooling with ice. The crystals were washed thoroughly with 60 ml. of cold water and again recrystallized from hot carbon tetrachloride. Yield=8.4 g. of white crystals, m.p. 36 C. The NMR and IR spectra indicated that the compound was CF SO -O-(CH -OSO CF Elementary analysis showed 32.5% F, 20.1% C, and 2.7% H. Theoretical values are 32.2% F, 20.3% C and 2.3% H.

72 g. of tetrahydrofuran, distilled over LiAlH was charged to a 125 ml. 3 neck round bottomed flask equipped with a stirrer and placed in an ice bath. 5.30 g. of tetramethylene bis(trifiuoromethane sulfonate) was then added and the polymerization carried out at 0 C. for 60 minutes. The flask was completely closed to the atmosphere. The di-cationically active polyether formed was then poured into an agitated solution of 40 ml. ethyl amine in 250 ml. of tetrahydrofuran at -60 C. After stirring for 5 minutes, the excess amine was removed by vacuum stripping. 30 g. of ion exchange resin, IRA-402 (Rohm & Haas), was added and the mixture was stirred for 18 hours at 25 C. The ion exchange resin was then removed by filtration and the solvent removed by vacuum stripping at 75 C. Yield of polyether di-secondary diamine was approximately 20%. Mn=5760; amine equivalent weight=l960. Amine groups per molecule=2.9.

Example 8 This example describes the determination of the terminating or non-terminating character of a series of anions.

Standard polymerization conditions were established as follows: ml. of anhydrous tetrahydrofuran containing a soluble salt was placed in a 250 ml. flask equipped with thermometer, stirrer and drying tube. The temperature was lowered to -5'0 C. and 5' ml. of redistilled (CF SO O was added. The amount of salt employed was equirnolar with (CF SO O, i.e. suflicient to reduce the functionality of the resulting poly(tetramethylene oxide) to as low as 1 if it were a terminating anion and suflicient to reduce markedly the molecular weight of said polymer. The temperature of the tetrahydrofuran solution was allowed. to warm to 0 C. (requiring 7 minutes) and held there for 10 minutes. Termination of polymerization was effected by addition of excess LiBr dissolved in tetrahydrofuran; this termination reaction served to append a Br atom to every cationic site persisting in the polymer solution. Thus determination of the molecular weight and percent of Br of the final polymer is indicative of the functionality of the M9 polymer. The results for the purified polymeric products are shown in Table I:

TABLE I Yield of Molecular *Functionality could not be determined directly, but from the known terminating ability of the Br ion, as well as the vastly reduced molecular (Iii/eight and yield, the monoiunctionality of the polymer can readily be educed.

It has been shown here that. of the ions tested, CF SO C10 SbCl BF and PF are nonterminating, and that MNO N and Br are terminating. Thus, in the class of catalysts capable of producing di-cationically active polymers, which is represented by the formula DQ, this example shows that Q may be any of the radicals CF SO ClO SbCl B'F or PF since these radicals do not cause termination of tetrahydrofuran polymerization when present in their anionic form. Q, however, may not be either of the radicals MnO NO;, or Br, since these radicals are shown to cause the termination of tetrahydrofuran polymerization, when present in their anionic form.

Example 9 This example describes the preparation of a complex salt and its use in converting tetrahydrofuran into a dicationically active polymer.

4.6 g. of CF SO F and 1.3 ml. of SbF were reacted in a sealed glass ampoule at room temperature. The CF SO F was used in excess here to act both as reactant and solvent. A crystalline light amber colored product resulted from the reaction. Excess of CF SO F was removed under vacuum. The resulting salt, which may be represented by the formula CF SO SbF was then used to polymerize tetrahydrofuran as follows:

100 ml. of tetrahydrofuran was distilled from LiAlH into a 200 ml. flask equipped with stirrer and thermometer. 3.7 g. of the above salt was added to the tetrahydrofuran at 22 C. At the end of 4.7 minutes the temperature had risen to 44 C. and was still rising, and the solution had become viscous. The reaction was terminated by the addition of 13 g. of LiBr, which served to attach Br atoms to all cationically active sites in the polymer solution. After removal of unreacted tetrahydrofuran the polymer was purified by extracting it with cyclohexane. The yield of purified polymer was 27%. Its molecular weight was 9570. Bromine analysis (2.07%) showed it to hear bromine atoms at each end of the polyether chain, thus clearly demonstrating the ability of this complex salt to convert tetrahydrofuran to a di-cationically active polymer.

Examples -12 pertain to the indirect method for making di-cationically active polymers from appropriate prepolymers.

Example 10 This example illustrates the conversion of an omega, omega-polyether glycol into a di-cationically active polymer and the subsequent conversion of this product into an omega,omega-polyether disecondary diamine.

The following were placed into a 1 liter flask equipped with stirrer and drying tube: 200 grams of poly(tetramethylene oxide) glycol (molecular weight=2700) and 600 ml. of methylene chloride This solution was cooled to -40 C. and 50 ml. of (CF SO O was added. The reactants were stirred for 2- /2 hours at a temperature of 30 C. to -40 C. During this period the glycol was converted to a di-cationically active product. The solution Was then rapidly poured into a mixture of 300 ml. of ethyl amine and 300 ml. of toluene maintained at 70 C. The combined solutions were allowed to warm to room temperature with overnight agitation. The volatile materials were removed, and the polymer was taken up in benzene, filtered, treated with a strongly basic ion exchange resin to remove catalyst residues, and dried. Analysis of the resulting polymer was as follows: number average molecular weight equals 2000; amine equivalent weight=981 (indicating 2.04 secondary amine groups per molecule); 1.59% N (indicating 2.27 nitrogen atoms per molecule).

Example 11 1314 g. of adipic acid, 874 g. of 1,4-butanediol and 1 g. of tetrabutyl tin were heated with agitation at 200-- 210 C. for 7 hours. The water of reaction was removed by azeotroping with heptane. 339 g. of water were collected during the 7 hours reaction period. The solvent and unreacted 1,4-butanediol were removed by vacuum stripping. Analysis of the polyester indicated an acid number of less than one and a hydroxyl equivalent weight of 1970.

4.9 ml. of (CF SO O, freshly distilled over P 0 and 100 ml. of anhydrous dichloromethane were charged to a 3 neck, 250 ml. round bottom flask equipped with stirrer, thermometer and dropping funnel. The temperature of the solution was lowered to 20 C., and a solution of 39.4 g. of the butanediol adipate polyester prepared above and 2.4 ml. of pyridine in 100 ml. of dichloromethane were added at 20 C. over a two hour period. The temperature of the mixture was then lowered to 50 C. and the solid pyridinium trifiuoromethane sulfonate salt removed by filtration. The filtrate containing the di-cationically active polyester was poured into an agitated solution of 25 g. of LiBr in 500 ml. tetrahydrofuran and stirred for 1 hour at room temperature. After washing the solution with 750 ml. of 5% KOH solution and 200 m1. of water and drying it with MgSO the solvent was removed by vacuum stripping at 70 C. The polymer was then extracted with boiling cyclohexane and the clear cyclohexane layer discarded. The residue was dissolved in 150 ml. of toluene, dried with anhydrous MgSO and centrifuged. The solvent was then removed by vacuum stripping at C. The infrared spectrum of the polymer (2() g. recovered yield) was devoid of any hydroxyl group absorption peak. Analysis showed 4.09% bromine. The theoretical bromine content, assuming two bromine end groups per molecule, is 3.94%.

Example 12 3.5 ml. of (CF SO O, freshly distilled over P 0 and ml. of dichloromethane were charged to a 3 neck, 250 ml. round bottom flask equipped with stirrer,

dropping funnel and thermometer. The temperature of the agitated solution was lowered to 20 C., and a solution of 39.4 g. vof the butanediol adipate polyester (prepared in Example 11) and 1.7 ml. of pyridine in 100 ml. of dichloromethane was added dropwise at 20 C. over a two hour period. The temperature of the mixture was lowered to 60 C. and the solid pyridinium trifluoromethane sulfonate salt removed by filtration. The filtrate containing the di-cationically active polyester was added to g. of freshly distilled tetrahydrofuran in a 500 ml., 2 neck round bottom flask equipped with a stirrer and a vacuum oulet tube. The temperature was allowed to rise to 25 C. and a vacuum was applied until the dichloromethane was removed. Polymerization was continued for 3 hours at 25 C. and then terminated by pouring the contents into a solution of 10 g. LiBr dissolved in 500 ml. of tetrahydrofuran. After washing this solution with 400 ml. of 5% KOH, then with 200 ml. of water and drying it with anhydrous MgSO the solvent was removed by vacuum stripping at 70 C. The polymer (50 g. recovered yield) was a viscous liquid at 70 C. and

was completely soluble at 25 'C. in cyclohexane, a nonsolvent for the polyester itself. Infrared analysis showed the presence of both ester and ether linkages and the absence of any hydroxyl groups. All evidence indicated that the product was a block copolymer containing central segments of polyester joined to polyether segments having terminal bromine groups.

Example 13 This example describes the preparation of another diester catalyst which is effective in the preparation of dicationically active polymers.

56.4 grams (0.2 moles) of trifluoromethanesulfonic anhydride was charged to a 500 ml. flask together with 100 ml. of methylene chloride, and the mixture was cooled to C. A mixture of 6.2 grams (0.1 mole) of ethylene glycol and 15.8 grams (0.2 moles) of pyridine in 150 ml. of methylene chloride was added slowly with stirring from a separatory funnel over a period of 2 /2 hours. The mixture was then stirred for 30 minutes at C. The precipitated pyridine acid salt was quickly filtered otf, and the filtrate in a stoppered flask was placed in a dry ice bath for 24 hours. The precipitate formed was filtered off and discarded. A 200 ml. portion of the filtrate was placed in a rotary film evaporator and the solvent was removed under vacuum at a temperature silghtly below 30 C. The residue was distilled and a water white fraction (6.1 grams) Was collected at 30- 32 C. and approximately 1 micron pressure. A second fraction having a light brown color (0.8 g.) was obtained at a higher temperature. The Water white fraction is identified as the dicster product, the reaction leading to the resulting diester being represented as CF SOzOCHzCH OS 020 F; 20 ms 63111305115 Various other embodiments of the present invention and additional uses therefore will be apparent to those skilled in the art without departing from the scope or spirit of this disclosure.

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:

1. A process for the preparation of a terminally polycationically active polymer which comprises reacting a polymer having at least two terminal radicals selected from the group consisting of hydroxyl, thiol, alkali metal alkoxide, alkali metal mercaptide, carboxylic acid, and sulfonic acid with (a) a mono-basic acid which is stronger than 100% sulfuric acid and which is capable of effecting the cationic polymerization of tetrahydrofuran without chain transfer, (b) an acyl halide thereof, (c) an anhydride thereof, or (d) an alkylene biester of the structure DZCH (A),,CH ZD, where Z is oxygen or sulfur, n is 0 0r 1, A is a divalent organic radical which is devoid of acetylenic and olefinic unsaturation and of alkylatable groups containing zerewitinoff hydrogen atoms, and D is the residue remaining after deletion of OH from the acid group of a monobasic acid defined in (a) above.

2. The process of claim 1 in which said polymer is a polyester.

3. The process of claim 1 in which said polymer is a polyether.

4. The process of claim 1 in which said polymer is a polyester having at least two terminal hydroxyl groups.

5. The process of claim 1 in which said polymer is a polyether having at least two terminal hydroxyl groups.

6. A process for the preparation of a terminally polycationically active polymer which comprises reacting a polymer having at least two terminal radicals selected from the group consisting of acyl bromide or acyl chloride with (a) a protonic acid which is stronger than 100% sulfuric acid and which is capable of effecting the cationic polymerization of tetrahydrofuran without chain transfer or (-b) a salt thereof.

7. The process of claim 6 in which said salt of the protonic acid is a silver salt.

References Cited UNITED STATES PATENTS 2,843,568 7/1958 Benning et al 260-775 3,214,421 10/ 1965 Mahan 26094.7

WILBERT J. BRIGGS, 811., Primary Examiner S. H. BLECH, Assistant Examiner US. Cl. X.R.

260-2, R, 2.5 R, 6, 2 BP, 32.6 R, 32.8 R, 33.6 R, 47 R, 67 FP, T, 77.5 D, 77.5 R, 78 SC, 78.4 D, 79, 79.3 R, 88.3 A, 91.1 S, 89.3, 89.5 S, 92.8 A, 93.5 A, 823, 829, 830 R, 849, 857, 860, 874 

